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Treatment Of Waste Liquid After Determination Of Josamycin, Theophylline And Paracetamol In Pharmaceutical Wastewater By High Performance Liquid Chromatography
来源: | Author:AUWII | time :2020-12-15 | 232 Browse: | 分享到:
Today I will share with you the topic of waste liquid treatment after the determination of josamycin, theophylline and paracetamol in pharmaceutical wastewater by high performance liquid chromatography. The high performance liquid chromatography mentioned in the article has been widely used in the bioenhanced degradation of pharmaceutical wastewater. Research, first, we briefly understand the background of this technology, and then we focus on how to collect the waste liquid after the test and the safe collection in the temporary storage process.

Today I will share with you the topic of waste liquid treatment after the determination of josamycin, theophylline and paracetamol in pharmaceutical wastewater by high performance liquid chromatography. The high performance liquid chromatography mentioned in the article has been widely used in the bioenhanced degradation of pharmaceutical wastewater. Research, first, we briefly understand the background of this technology, and then we focus on how to collect the waste liquid after the test and the safe collection in the temporary storage process.

 

We know that the residual pharmaceutical components in the pharmaceutical wastewater are causing more and more serious environmental pollution, and the treatment of pharmaceutical wastewater has become a very important aspect of environmental protection. Josamycin is a broad-spectrum antibiotic of big bad lactones, which is difficult to be biodegraded; theophylline is a meso-xanthine derivative and a heterocyclic compound which is difficult to biodegrade; Paracetamol (paracetamol) is acetaminophen, which is also a relatively difficult substance to be biodegraded. Aiming at these kinds of pharmaceutical pollutants that are difficult to degrade in pharmaceutical wastewater.

 

Treatment of waste liquid after determination of josamycin, theophylline and paracetamol in pharmaceutical wastewater by high performance liquid chromatography

 

At present, there is a proper solution. A patent has established a high performance liquid chromatography method for the simultaneous determination of josamycin, theophylline, and paracetamol remaining in pharmaceutical wastewater. The sample is subjected to chromatographic analysis after solid phase extraction. Chromatographic conditions used: chromatographic column is HypersilODS column (4.6mmi.d.×200mm); mobile phase A is 0.025mol/L KH2PO4H3PO4 buffer (pH2.75), mobile phase B is methanol; gradient elution; UV detection The wavelengths are 230nm (josamycin), 272nm (theophylline), 243nm (paracetamol). The recovery rates of the three drugs in pharmaceutical wastewater were all higher than 93%, the relative standard deviation (n=6) was less than 2.1%, and the detection limit (S/N=3) was not higher than 1.0μg/L.

 

It is gratifying to have a proper solution, but how should the waste liquid after the experiment be handled? How can the quasi-experimental solvent during the experiment not be contaminated by other impurities? The next step will be handled by us. The green laboratory series products launched by AUWII Instrument Co., Ltd. provide green and safe solutions for the safe sealing of laboratory solvent bottles and the collection of laboratory waste liquids, protecting the laboratory environment, Take care of the health of laboratory personnel.

 

Among them, the SE series of solvent safety caps can be used for the safe sealing of solvent bottles in liquid chromatography, automatic solid phase extraction, pressurized solvent extraction instruments and other instruments and equipment, and can efficiently filter dust in the air when the instruments are working to prevent solvent pollution. To ensure the accuracy of the analysis results, when the instrument stops working, it can prevent the solvent from volatilizing out through the air inlet to protect the laboratory environment from pollution. There are also intubation waste collection devices and funnel waste collection devices for waste liquids. The device can be used for the collection of waste liquid discharged by spectrometer, liquid chromatograph, mass spectrometer and pretreatment equipment in the laboratory. The exhaust gas filter can efficiently adsorb the volatilized harmful gas, protect the laboratory environment and protect the health of the experimenter. Liquid level alarm prevents liquid overflow. Various types of secondary containers prevent secondary pollution and meet regulatory requirements.